Baneh Fruits (Pistacia Atlantica) improved Some Biochemical Parameters in Wistar Male Rats
Mohsen Jafarian Dehkordi(PhD)1, Reza Azadbakht(MD)2, Reza Fathi Hafshejani(MD)2, Soudeh Khanamani Falahati-pour (PhD)3, Sakineh Khanamani Falahati-pour (PhD)4*
1 Assistant Professor, Department of Clinical pathology, Faculty of Veterinary Medicine, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran
2 Graduate of Veterinary, Faculty of Veterinary Medicine, University of Islamic Azad of Shahrekord, Shahrekord, Iran
3 Pistachio Safety Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
4 Department of Pharmacology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Introduction: In traditional medicines, almost all Asian countries, particularly Iran, consider plants for therputical purposes. This study assessed the impact of the Baneh Fruits (Pistacia Atlantica) hydroethanolic extract on certain enzymes and biochemical elements in rats.
Materials and Methods: 200 and 400 mg/kg of the extract were given orally once a day for 28 days to two rat groups, each with eight animals. The control group was given only distilled water. Under chloroform anesthesia, the rats fasted overnight were dissected on the 29th day. Then, their blood was directly taken from their hearts. In the next step, some liver biochemical parameters including aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma-glutamyl transferase (GGT), total bilirubin, biochemical parameters of kidney including blood urea nitrogen (BUN), creatinine, urea, and metabolic parameters including fasting plasma glucose (FPG), cholesterol, triglycerides, and high-density lipoprotein cholesterol (HDL-C) were measured in the collected blood serums.
Results: The plant fruit extract decreased significantly the serum concentrations of triglycerides, cholesterol, AST, creatinine, and total bilirubin in the two doses (p<0.05). The 200 mg/kg dose decreased BUN and urea concentrations and increased HDL-C concentration significantly (p<0.05). While only a dose of 400mg/kg of the extract decreased the GGT level significantly (p<0.05).
Conclusions: The hypocholesterolemic, hypotriglyceridemic, and hypo bilirubinemic impact of the extract coupled with the decreased AST activity indicated that the Baneh fruit may be beneficial in controlling hyper-triglyceridemia and hyper-cholesterolemia.
►Please cite this article as follows:
Jafarian Dehkordi M, Azadbakht R, Fathi Hafshejani R, Khanamani Falahatipour S, Khanamani Falahati-pour S. Baneh Fruits (Pistacia Atlantica) improved Some Biochemical Parameters in Wistar Male Rats. Pistachio and Health Journal. 2021; 4 (2): 4-12.